Explorar skills

Compare ENCODE experiments across different biosamples, tissues, or cell lines to identify tissue-specific regulatory patterns. Use when the user wants cross-tissue comparison, cell-type comparison, tissue-specific elements, differential chromatin, biosample matching, disease vs normal comparison, developmental time course, constitutive vs variable regulation, or multi-tissue data availability map

Coordinate software development work by analyzing requirements, delegating tasks to specialized sub-agents (developer, code-reviewer, tester), and synthesizing their work into cohesive deliverables. Use this for complex projects that require multiple specialized perspectives.

Use to conduct STRIDE threat modeling for a system or feature design.

Use to verify a feature/story meets all Definition of Done criteria before marking complete.

Use before starting delivery work. Pre-implementation validation checklist to ensure readiness.

Query gnomAD (Genome Aggregation Database) for population allele frequencies, gene constraint scores, and variant annotations to interpret ENCODE regulatory variants. Use when the user needs allele frequencies for variants in ENCODE regulatory elements, wants to assess gene constraint (pLI, LOEUF) for ENCODE target genes, needs population-specific frequencies for GWAS variants overlapping cCREs, w

Explainability (XAI) audit for products containing AI components. Five-stage tier-scaled check: risk classification, stakeholder×question matrix, fidelity audit, system card, recourse path. Honest about what was validated functionally vs what needs user testing.

Use when real user interviews aren't possible (solo/hobby/dogfood projects) but persona work is still needed. Enforces epistemic discipline: adversarial spectrum, pre-committed stop conditions, speculation tagging. NOT a substitute for /mycelium:user-interview when real users are available.

Generate 3D models from text or images via 5 providers: Meshy (text-to-3D, texturing, batch), fal.ai Hunyuan3D Pro ($0.225, PBR), WaveSpeedAI Rapid ($0.0225, bulk), Trellis 2 (poly control), and Local Depth (free offline ONNX depth maps + mesh). Includes GLB viewer. Triggers on 3D model, image to 3D, GLB, depth map, text to 3D, texturing, 3D asset, Meshy, Hunyuan.

Has description but no name field.

Build or update a CONTEXT.md domain glossary for the current project. Establishes shared vocabulary with term definitions, avoid-aliases, and relationships so agents use consistent, concise language. This skill should be used when starting a new project, when domain terminology is inconsistent across sessions, when the user says "build a glossary", "define our terms", "shared vocabulary", or "doma

Design and prototype in Paper Design (app.paper.design) — read/write designs via MCP, convert to React/Tailwind code, import HTML/CSS, sync design tokens. Also covers Paper Shaders (@paper-design/shaders-react) — 30+ shader React components (mesh gradient, fluted glass, liquid metal, god rays, halftone, grain gradient, pulsing border). Pairs with minoan-frontend-design for creative direction. Trig