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Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed

Build reproducible scientific documents, presentations, and websites with Quarto supporting R, Python, Julia, and Observable JS. Use when creating reproducible reports with Quarto.

Designs and builds ETL/ELT data pipelines. Takes data sources, destination, transformation requirements. Generates pipeline code (Python/SQL), scheduling config, error handling, monitoring setup, and data quality checks. Outputs data-pipeline-spec.md + implementation files.

SDK do Azure Container Registry para Python. Gerencia imagens de contêiner, artefatos e repositórios. Gatilhos incluem 'azure-containerregistry', 'ContainerRegistryClient', 'container images', 'docker registry', 'ACR'.

Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools. Use when building MCP servers to integrate external APIs or services, whether in Python (FastMCP) or Node/TypeScript (MCP SDK).

Build reproducible bioinformatics pipelines with Snakemake using rules, wildcards, and automatic dependency resolution. Use when creating Python-based workflows, automating multi-step analyses with make-like dependency tracking, or running pipelines on HPC clusters with SLURM.

Build automated AI workflows combining multiple models and services. Patterns: batch processing, scheduled tasks, event-driven pipelines, agent loops. Tools: inference.sh CLI, bash scripting, Python SDK, webhook integration. Use for: content automation, data processing, monitoring, scheduled generation. Triggers: ai automation, workflow automation, batch processing, ai pipeline, automated content,

Creates devcontainers with Claude Code, language-specific tooling (Python/Node/Rust/Go), and persistent volumes. Use when adding devcontainer support to a project, setting up isolated development environments, or configuring sandboxed Claude Code workspaces.

Out-of-the-box Seedance 2.0 API skill — just one API key to generate AI videos. Builds storyboards, generates reference images with Seedream 4.5, submits video tasks, and polls results. Supports both MCP and standalone Python script mode. Use when the user mentions seedance, AI video, storyboard, or video generation.

Use when you need exact symbolic math in Python — algebra, calculus, equation solving, symbolic linear algebra, or code generation via lambdify/LaTeX. Prefer NumPy or SciPy when floating-point approximations are sufficient.

World-class data science skill for statistical modeling, experimentation, causal inference, and advanced analytics. Expertise in Python (NumPy, Pandas, Scikit-learn), R, SQL, statistical methods, A/B testing, time series, and business intelligence. Includes experiment design, feature engineering, model evaluation, and stakeholder communication. Use when designing experiments, building predictive m

Esta skill é utilizada para analisar binários, executáveis ou bytecode, visando compreender sua funcionalidade. Ela é acionada por termos como 'binary', 'executable', 'ELF' e direciona para sub-skills de triagem, análise estática/dinâmica, síntese ou configuração de ferramentas.