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Build Unity games with optimized C# scripts, efficient rendering,

Provides a structured workflow for planning and executing code reviews like a senior engineer. Use when asked to review code, PRs, or plan a code review task.

Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Li & Hart 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving 2-3x sensitivity over MAGeCK / STARS / edgeR / RIGER on drug screens, pe

Guides the design and structuring of workflow-based Claude Code skills with multi-step phases, decision trees, subagent delegation, and progressive disclosure. Use when creating skills that involve sequential pipelines, routing patterns, safety gates, task tracking, phased execution, or any multi-step workflow. Also applies when reviewing or refactoring existing workflow skills for quality.

Security audit for Android projects. Checks OWASP-oriented client-side risks, manifest exposure, hardcoded secrets, WebView handling, storage posture, and build obfuscation evidence. Triggers on: "security", "OWASP", "permissions", "encryption", "WebView", "certificate pinning".

Differentially methylated region (DMR) detection using methylKit tiles, bsseq BSmooth, and DMRcate. Use when identifying contiguous genomic regions with methylation differences between experimental conditions or cell types.

Implemente fluxos de trabalho GitOps com ArgoCD e Flux para implantações automatizadas e declarativas no Kubernetes com reconciliação contínua. Use ao implementar práticas GitOps, automatizar implantações no Kubernetes ou configurar o gerenciamento de infraestrutura declarativa.

Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.

Visual inspection of live websites to find and fix design issues. Use when reviewing UI layout/design, checking responsive design visually, detecting visual inconsistencies, or diagnosing CSS/accessibility problems at the source code level. Not for automated E2E testing.

Network utility for reading and writing data across TCP/UDP connections, port scanning, file transfers, and backdoor communication channels. Use when: (1) Testing network connectivity and port availability, (2) Creating reverse shells and bind shells for authorized penetration testing, (3) Transferring files between systems in restricted environments, (4) Banner grabbing and service enumeration, (

Execute implementation tasks from design documents using markdown checkboxes. Use when (1) implementing features from feature-design-assistant output, (2) resuming interrupted work, (3) batch executing tasks. Triggers on 'start implementation', 'run tasks', 'resume'.

Soluciona e resolve problemas com os SDKs de Mensagens do Azure para Event Hubs e Service Bus, cobrindo falhas de conexão, erros de autenticação, processamento de mensagens e configuração do SDK.