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Find restriction enzyme cut sites in DNA sequences using Biopython Bio.Restriction. Search with single enzymes, batches of enzymes, or commercially available enzyme sets. Returns cut positions for linear or circular DNA. Use when finding restriction enzyme cut sites in sequences.

Analyzes time-to-event data using Kaplan-Meier curves, log-rank tests, and Cox proportional hazards regression with lifelines. Builds survival models from clinical and omics features. Use when predicting patient survival or modeling time-to-event outcomes.

Generate images with Flux 2 Klein (Black Forest Labs' distilled fast variant of Flux 2) on RunComfy — bundled with the model's documented prompting patterns so the skill gets sharper output than naive prompting against the same model. Documents Flux 2 Klein's strengths (sub-second latency, multi-reference brand styling, declarative subject-first prompts), the step-count strategy (4–8 for fast iter

Validate PCR primers for specificity, dimers, hairpins, and secondary structures using primer3-py thermodynamic calculations. Check self-complementarity, heterodimer formation, and 3' stability. Use when validating primer specificity and properties.

You are an error tracking and observability expert specializing in implementing comprehensive error monitoring solutions. Set up error tracking systems, configure alerts, implement structured logging,

Harmony batch correction for scRNA-seq and other omics. Removes batch effects from PCA embeddings while preserving biology. Run after PCA, before UMAP. Scales to millions of cells. Python (harmonypy, scanpy) and R (Seurat).

Padrão para interagir eficazmente com usuários para coletar informações ou obter decisões. Utilize quando precisar de entrada do usuário.

Apideck Unified API integration patterns for C# and .NET. Use when building integrations with accounting software (QuickBooks, Xero, NetSuite), CRMs (Salesforce, HubSpot, Pipedrive), HRIS platforms (Workday, BambooHR), file storage (Google Drive, Dropbox, Box), ATS systems (Greenhouse, Lever), e-commerce, or any of Apideck's 200+ connectors using .NET. Covers the ApideckUnifySdk NuGet package, aut

When the user wants to create, optimize, or structure a changelog or release notes page. Also use when the user mentions "changelog," "release notes," "what's new," "updates," "product updates," "version history," or "changelog.yourdomain.com." For sitewide page planning, use website-structure.

Design production-ready database schemas for SQL and NoSQL databases. Use when user asks to "design schema", "create tables", "database design", "ERD", "data model", or when starting a project that needs database structure. Triggers on "normalize", "migration plan", "index strategy", "테이블 설계".

Ceridian Dayforce integration via Apideck's HRIS unified API — same methods work across every connector in HRIS, switch by changing `serviceId`. Use when the user wants to read or sync employees, departments, payrolls, and time-off records in Ceridian Dayforce. Routes through Apideck with serviceId "ceridian-dayforce".

Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro R