bg-szy

Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test linea

Esta skill analisa listagens de concorrentes na Amazon por ASIN, gerando inteligência competitiva estruturada e oportunidades estratégicas de entrada no mercado. Ela auxilia a entender produtos de alto desempenho, identificar lacunas de mercado e necessidades não atendidas dos compradores.

Fluxo de trabalho guiado para implementar protótipos de design HTML como componentes React de produção, com estilo glassmorphism e aplicação de padrões de qualidade. Utilize ao converter protótipos de design em código de produção.

This skill should be used when the user asks to "create a proposal", "design a report", "make a one-pager", "build a PDF", "create a newsletter", "design slides", "make event materials", "design a flyer", or needs help with print-ready HTML documents. Provides brand configuration, CSS patterns for print layout, and document design best practices.

Analyzes base-editing screens for variant function. Covers library design (Sanson 2020 GRACE, Hanna 2021 BRCA1/2 SNV scanning, Cuella-Martin 2021), CBE vs ABE chemistry choice (BE3/BE4 vs ABE7.10/ABE8.20/ABE8e), editing-window math (positions 4-8 from PAM-distal end, wider for ABE8e), bystander-edit quantification and the variant-call ambiguity it creates, sgRNA-efficiency filtering before hit cal

Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server. Returns 25+ fields per paper including methods, results, sample sizes, quality scores, and conclusions. Use for literature reviews, evidence synthesis, and finding experimental details not available in abstracts alone.

End-to-end Ribo-seq analysis from FASTQ to translation efficiency and ORF detection. Use when analyzing ribosome profiling data to study translation.

Enforces TDD order in TASKS.md - Tests MUST be marked complete before Implementation tasks. Blocks violations in real-time.

Optimize website and web application performance including loading speed, Core Web Vitals, bundle size, caching strategies, and runtime performance

Serena MCP for project memory and code navigation. Use when managing Serena memories, navigating symbols, performing intelligent refactoring, or maintaining context/continuity across AI agent sessions.

Build Manhattan, Miami, QQ, and locuszoom-style regional plots from GWAS, TWAS, PWAS, and QTL summary statistics with correct genomic-inflation diagnostics, multi-trait overlays, lead-SNP labeling, and LD-aware regional rendering. Use when visualizing association results across the genome, comparing two traits, computing genomic inflation lambda, or zooming into a locus with LD coloring.

Auto-invoke when reviewing HTML head, meta tags, or Next.js page components. Enforces semantic HTML and search optimization.