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Audit npm dependencies for security vulnerabilities, outdated packages, and unused dependencies. Use when checking for security issues, updating packages, or cleaning up dependencies.

Checkpoint framework and validation rules for all agents. Ensures quality gates are passed at every stage of development.

Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against best practices".

Creates reproducible Jupyter notebooks for bioinformatics analysis with parameterization using papermill. Use when generating automated analysis reports, running notebook-based pipelines, or creating shareable computational notebooks.

Comprehensive frontend development skill for building modern, performant web applications using ReactJS, NextJS, TypeScript, Tailwind CSS. Includes component scaffolding, performance optimization, bundle analysis, and UI best practices. Use when developing frontend features, optimizing performance, implementing UI/UX designs, managing state, or reviewing frontend code.

Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity satu

Engenheiro UI/UX Sênior. Arquiteta interfaces digitais superando vieses padrão de LLMs, aplicando regras baseadas em métricas, arquitetura de componentes rigorosa, aceleração de hardware CSS e engenharia de design equilibrada.

Production-ready single-cell and expression matrix analysis using scanpy, anndata, and scipy. Performs scRNA-seq QC, normalization, PCA, UMAP, Leiden/Louvain clustering, differential expression (Wilcoxon, t-test, DESeq2), cell type annotation, per-cell-type statistical analysis, gene-expression correlation, batch correction (Harmony), trajectory inference, and cell-cell communication analysis. NEW

View, query, and understand VCF/BCF variant files using bcftools and cyvcf2. Use when inspecting variants, extracting specific fields, or understanding VCF format structure.

Validate, gap-fill, and curate genome-scale metabolic models using memote for quality scores and COBRApy for manual curation. Ensure models meet SBML standards and produce biologically meaningful predictions. Use when improving draft models or preparing models for publication.

Automated code review analyzing security, performance, maintainability, and test coverage. Activated during code reviews or when conducting analysis.

Generate unique personalized first lines for hundreds of prospects using company news, LinkedIn activity, and mutual connections. Saves 10+ hours of manual research per campaign. Use when you need personalized outreach at volume.