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Use when writing or changing tests, adding mocks, or tempted to add test-only methods to production code - prevents testing mock behavior, production pollution with test-only methods, and mocking without understanding dependencies

Estimates required sample sizes for differential expression, ChIP-seq, methylation, and proteomics studies. Use when budgeting experiments, writing grant proposals, or determining minimum replicates needed to achieve statistical significance for expected effect sizes.

Analyze raw prompts, identify intent and gaps, match ECC components (skills/commands/agents/hooks), and output a ready-to-paste optimized prompt. Advisory role only — never executes the task itself. TRIGGER when: user says \"optimize prompt\", \"improve my prompt\", \"how to write a prompt for\", \"help me prompt\", \"rewrite this prompt\", or explicitly asks to enhance prompt quality. Also trigge

Network architecture, troubleshooting, and infrastructure patterns. Use

Align DNA short reads to reference genomes using bwa-mem2, the faster successor to BWA-MEM. Use when aligning DNA short reads to a reference genome.

When the user wants to create, optimize, or audit blog index or listing page structure (not a single post). Also use when the user mentions "blog page," "blog index," "blog layout," "content hub," "blog homepage," "blog listing," "subdomain vs subdirectory," "blog structure," or "blog SEO." For single post page SEO and schema, use article-page-generator.

Official Google SEO guide covering search optimization, best practices, Search Console, crawling, indexing, and improving website search visibility based on official Google documentation

Reads, queries, and writes bigWig indexed binary signal tracks (coverage, fold-change, conservation, methylation-rate) with pyBigWig (Python) and the UCSC Kent tools (bedGraphToBigWig, bigWigToBedGraph, bigWigInfo, bigWigSummary, bigWigAverageOverBed) and deepTools (multiBigwigSummary, computeMatrix, bigwigCompare). Covers the central trap that a wide query returns a precomputed zoom-level summary

End-to-end CRISPR experiment design from target selection to delivery-ready constructs. Covers guide RNA design, off-target assessment, and specialized editing strategies including knockouts, base editing, and HDR knockins. Use when designing complete CRISPR editing experiments for gene knockout, correction, or tagging.

Manage and monitor UniFi sites across your account. View site details, organization structure, and multi-site overview for centralized infrastructure management.

Generate images using Nano Banana Pro (Gemini 3 Pro Preview). Use when creating app icons, logos, UI graphics, marketing banners, social media images, illustrations, diagrams, or any visual assets. Supports reference images for style transfer and character consistency. Triggers include phrases like 'generate an image', 'create a graphic', 'make an icon', 'design a logo', 'create a banner', 'same s

Comprehensive skill for interacting with Grafana's HTTP API to manage dashboards, data sources, folders, alerting, annotations, users, teams, and organizations. Use when Claude needs to (1) Create, read, update, or delete Grafana dashboards, (2) Manage data sources and connections, (3) Configure alerting rules, contact points, and notification policies, (4) Work with folders and permissions, (5) M