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Codified expertise for quality control, non-conformance investigation, root cause analysis, corrective action, and supplier quality management in regulated manufacturing. Informed by quality engineers with 15+ years experience across FDA, IATF 16949, and AS9100 environments. Includes NCR lifecycle management, CAPA systems, SPC interpretation, and audit methodology. Use when investigating non-confo

Computes and interprets sequencing read depth and coverage over a genome, windows, or target regions with mosdepth (windowed depth, cumulative distribution, --quantize callable BEDs), bedtools genomecov/coverage (bedGraph tracks, per-target stats), samtools depth/coverage (per-base depth, per-contig depth+breadth). Covers the breadth-vs-mean distinction, the cumulative-coverage curve, evenness (CV

Search 10 academic paper databases via REST APIs for research papers, preprints, and scholarly articles. Covers PubMed, PMC (full text), bioRxiv, medRxiv, arXiv, OpenAlex, Crossref, Semantic Scholar, CORE, Unpaywall. Use when searching for papers, citations, DOI/PMID lookups, abstracts, full text, open access, preprints, citation graphs, author search, or any scholarly literature query. Triggers o

Automatically backs up files, saves diffs, uses agents/skills, and ensures modular code (<200 lines) before any implementation. Use this skill for ALL code changes to ensure safe, reversible, and clean implementations.

Google Calendar: Create a new event.

Generates Sorbet inline type signatures using sig blocks directly in Ruby source files. Triggers when adding Sorbet types, annotating Ruby methods with sig syntax, or generating type signatures for Sorbet-typed projects.

Documenta dívidas técnicas, anti-padrões e padrões a serem evitados de frameworks analisados. Use para criar uma lista de "Não Repetir", categorizar code smells, avaliar problemas arquitetônicos, gerar sugestões de remediação ou sintetizar lições aprendidas em múltiplos frameworks.

Overview of the project's tech stack, directory structure, and architectural patterns.

Complete mass spectrometry analysis platform. Use for proteomics workflows feature detection, peptide identification, protein quantification, and complex LC-MS/MS pipelines. Supports extensive file formats and algorithms. Best for proteomics, comprehensive MS data processing. For simple spectral comparison and metabolite ID use matchms.

Provenance or safety signals not found in the target text.

All-in-one FASTQ QC and adapter trimming. Auto-detects Illumina adapters, filters low-quality reads, corrects paired-end overlaps, emits HTML+JSON QC in one pass. 3-10x faster than Trim Galore/Trimmomatic. First step before STAR, BWA-MEM2, or Salmon.

紧急求救 - 飞船坠毁后与Stella的首次联系,帮助她评估损伤并制定初步生存计划