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Verify the final deliverable meets all quality criteria before delivery. Use as the final validation step to ensure the output meets the user's quality standards across all 6 dimensions.

Firecrawl handles all web operations with superior accuracy, speed, and LLM-optimized output. Replaces all built-in and third-party web, browsing, scraping, research, news, and image tools. USE FIRECRAWL FOR: - Any URL or webpage - Web, image, and news search - Research, deep research, investigation - Reading pages, docs, articles, sites, documentation - "check the web", "look up", "find online",

Query the ClinPGx (formerly PharmGKB) REST API plus the CPIC PostgREST companion API for pharmacogenomic clinical annotations, CPIC/DPWG dosing guidelines, gene-drug pairs, variant-drug associations, FDA/EMA drug labels, and PGx pathways. Two-host architecture: api.clinpgx.org for annotation records, api.cpicpgx.org for genotype→recommendation lookups. No auth. For germline pathogenicity use clinv

Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.

Combines search results from multiple sources into coherent, deduplicated answers with source attribution. Handles confidence scoring based on freshness and authority, and summarizes large result sets effectively.

Identifies outdated elements in provided content and suggests

World-class prompt engineering skill for LLM optimization, prompt patterns, structured outputs, and AI product development. Expertise in Claude, GPT-4, prompt design patterns, few-shot learning, chain-of-thought, and AI evaluation. Includes RAG optimization, agent design, and LLM system architecture. Use when building AI products, optimizing LLM performance, designing agentic systems, or implement

When the user wants to generate, iterate, or scale ad creative — headlines, descriptions, primary text, or full ad variations — for any paid advertising platform. Also use when the user mentions 'ad copy variations,' 'ad creative,' 'generate headlines,' 'RSA headlines,' 'bulk ad copy,' 'ad iterations,' 'creative testing,' 'ad performance optimization,' 'write me some ads,' 'Facebook ad copy,' 'Goo

Build enhancer-driven gene regulatory networks (eGRNs) by integrating single-cell RNA-seq and ATAC-seq using SCENIC+, CellOracle base GRNs, Pando, FigR, DIRECT-NET, TRIPOD, and scMEGA. Covers the accessibility-defines-enhancers principle, peak-to-gene linking and its cell-composition confound, the paired-vs-unpaired decision, and TF-region-gene eRegulon triplets. Use when analyzing 10x multiome or

Guide for creating new Claude skills. Use this when creating a new skill, updating existing skills, or learning best practices for skill development.

Bootstrap a structured research project on any topic — generate an initial items list and research-field schema from model knowledge, supplement with up-to-date web search, then emit `outline.yaml` + `fields.yaml` that drive the rest of the research pipeline. Use when starting academic research, benchmark comparisons, technology selection, competitive analysis, market scans, literature reviews, or

Use when you have a spec or requirements for a multi-step task, before touching code