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Build maximum likelihood phylogenetic trees using IQ-TREE2 and RAxML-NG with expert model selection, branch support assessment, and topology testing. Use when inferring publication-quality ML trees, selecting substitution models, interpreting bootstrap and concordance factor support, or running partitioned phylogenomic analyses.

Postgres performance optimization and best practices from Supabase. Use this skill when writing, reviewing, or optimizing Postgres queries, schema designs, or database configurations.

Extract comprehensive JSON design specifications from visual sources including Figma exports, UI mockups, screenshots, or live website captures. Produces W3C DTCG-compliant output with component trees, suitable for code generation, design documentation, and developer handoff.

AI-assisted pair programming with multiple modes (driver/navigator/switch), real-time verification, quality monitoring, and comprehensive testing. Supports TDD, debugging, refactoring, and learning sessions. Features automatic role switching, continuous code review, security scanning, and performance optimization with truth-score verification.

This skill should be used when the user asks to "implement LLM-as-judge", "compare model outputs", "create evaluation rubrics", "mitigate evaluation bias", or mentions direct scoring, pairwise comparison, position bias, evaluation pipelines, or automated quality assessment.

Pre-commit hooks framework for multi-language code quality automation. USE WHEN setting up pre-commit OR configuring git hooks OR adding linting OR code formatting OR security scanning OR Terraform validation OR Kubernetes manifests OR Helm charts OR Python linting OR JavaScript formatting. Manages .pre-commit-config.yaml, hook installation, and CI integration.

DBOS TypeScript SDK for building reliable, fault-tolerant applications with durable workflows. Use this skill when writing TypeScript code with DBOS, creating workflows and steps, using queues, using DBOSClient from external applications, or building applications that need to be resilient to failures.

Create and edit Obsidian Bases (.base files) with views, filters, formulas, and summaries. Use when working with .base files, creating database-like views of notes, or when the user mentions Bases, table views, card views, filters, or formulas in Obsidian.

Intelligent web scraper with content extraction, multiple output formats, and error handling

Implement distributed tracing with Jaeger and Tempo to track requests across microservices and identify performance bottlenecks. Use when debugging microservices, analyzing request flows, or implementing observability for distributed systems.

Creates sashimi plots showing RNA-seq read coverage and splice junction counts using ggsashimi or rmats2sashimiplot. Visualizes differential splicing events with grouped samples and junction read support. Use when visualizing specific splicing events or validating differential splicing results.

Document architecture decisions with ADR (Architecture Decision Records). Use when making significant technical decisions, choosing between alternatives, or when onboarding needs context on past decisions.