Dados e Análise

Investment management skill — portfolio construction, analysis, and execution. Compounds finance-substrate (accounting/tax) + wealth-management (projections/goals) into a full financial framework. Covers traditional investing (stocks, ETFs, bonds), alternatives (crypto, prediction markets, real estate, VC), quantitative analytics (factor models, Monte Carlo, optimization), and platform integration

Quality control and assessment for proteomics data. Use when evaluating proteomics data quality before downstream analysis. Covers sample metrics, missing value patterns, replicate correlation, batch effects, and intensity distributions.

Implement PCI DSS compliance requirements for secure handling of payment card data and payment systems. Use when securing payment processing, achieving PCI compliance, or implementing payment card security measures.

Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract, SES), k-me

Microscopy data management platform. Access images via Python, retrieve datasets, analyze pixels, manage ROIs/annotations, batch processing, for high-content screening and microscopy workflows.

Use when suggesting APIs for a project, looking for free data sources, building weekend projects that need external data, or when the user needs weather, news, finance, sports, ML, or entertainment data without paid subscriptions

Crie serviços Azure Cosmos DB NoSQL com Python/FastAPI, seguindo padrões de produção. Abrange configuração de cliente com autenticação dupla, operações CRUD, estratégias de chave de partição e padrões TDD.

Detect transcription factor binding sites through footprinting analysis in ATAC-seq data using TOBIAS. Use when identifying TF occupancy patterns within accessible regions, as TF binding protects DNA from Tn5 cutting.

Comprehensive variant annotation using bcftools annotate/csq, VEP, SnpEff, and ANNOVAR. Add database annotations, predict functional consequences, and assess clinical significance. Use when annotating variants with functional and clinical information.

Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables. Use when batch-converting Ensembl IDs to other namespaces (HGNC, RefSeq, UniProt, Entrez), pulling gene coordinate tables for thousands of genes, building ortholog wide-tables across species, or replacing slow Ensembl REST loops with one-shot bulk export. E

Esta skill é utilizada para gerar visões de arquitetura, grafos de dependência de serviços, mapear fluxos de requisição, exibir topologias de eventos, agrupar serviços por domínio e visualizar arquiteturas. Também é aplicável para análise de arquitetura entre repositórios, mapeamento de serviços e visualização arquitetural.

Mine for hidden bugs that pattern-based auditors miss. 7 analysis lenses: assumptions, state machines, boundary conditions, data lifecycle, error paths, time-dependent behavior, and platform divergence. Triggers: "prospect for bugs", "find hidden bugs", "assumption audit", "what could go wrong", "bug prospector".