Desenvolvimento

Habilidade do Claude Code para detectar padrões de testes instáveis que causam falhas intermitentes na CI.

Bootstrap a project's structure — convention folders, a CLAUDE.md contract (test command, run/demo command, blueprint format), and a starter spec with the "Done when" format. Run once per project.

Constant-time testing detects timing side channels in cryptographic code. Use when auditing crypto implementations for timing vulnerabilities.

Change phases in the GitHub Elements workflow by closing current thread and opening the next. Use for DEV→TEST, TEST→REVIEW, REVIEW→merge transitions, or demotions. Do not use for saving progress.

Fetch up-to-date library documentation via Context7 API. Use PROACTIVELY when: (1) Working with ANY external library (React, Next.js, Supabase, etc.) (2) User asks about library APIs, patterns, or best practices (3) Implementing features that rely on third-party packages (4) Debugging library-specific issues (5) Need current documentation beyond training data cutoff (6) AND MOST IMPORTANTLY, when

Bypass SiteGround caching (SG CachePress + LiteSpeed) for WordPress development. Adds cache-busting code to child themes for real-time development testing.

Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for bet

Use when implementing bug fixes, features, or any code changes where test-first development is appropriate.

Test whether two traits share a causal variant at a genomic locus using Bayesian colocalization with coloc. Computes posterior probabilities for shared vs distinct causal variants between GWAS and eQTL signals. Use when determining if a GWAS signal and an eQTL share the same causal variant.

Identifies non-coding RNAs (tRNA, rRNA, snoRNA, snRNA, riboswitches, sRNAs) using Infernal covariance-model search against Rfam, tRNAscan-SE 2.0 for tRNA, barrnap for rRNA, and ARAGORN for tmRNA, plus the small-RNA-seq boundary for miRNA and the transcript-assembly boundary for lncRNA. Covers the structure-conserved-not-sequence-conserved principle (why BLAST fails), GA-threshold and clan-competit

Alpha and beta diversity analysis for microbiome data. Calculate within-sample richness, evenness, and between-sample dissimilarity with phyloseq and vegan. Use when comparing community composition across samples or testing for group differences in microbiome structure.