Design e Frontend

Design microservices architectures with service boundaries, event-driven communication, and resilience patterns. Use when building distributed systems, decomposing monoliths, or implementing microservices.

Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use

Crie componentes React, implemente layouts responsivos e gerencie interações do usuário.

Use when writing or reviewing TypeScript code. Enforces strict mode standards, explicit typing, and best practices. Prevents 'any' types, @ts-ignore comments, and non-null assertions. This is a COMPREHENSIVE skill - consult the detailed guides before writing any TypeScript code.

Conjunto de ferramentas para criar artefatos HTML elaborados e multi-componentes para claude.ai, utilizando tecnologias web frontend modernas (React, Tailwind CSS, shadcn/ui). Use para artefatos complexos que exigem gerenciamento de estado, roteamento ou componentes shadcn/ui, não para artefatos HTML/JSX simples de arquivo único.

Creates structured hiring scorecards for any role. Takes job title, requirements, and team context. Generates comprehensive scorecard with weighted scoring rubric, interview questions per competency, evaluation matrix, red/green flags, and reference check questions.

This skill should be used when the user asks to "add MCP server", "integrate MCP", "configure MCP in plugin", "use .mcp.json", "set up Model Context Protocol", "connect external service", mentions "${CLAUDE_PLUGIN_ROOT} with MCP", or discusses MCP server types (SSE, stdio, HTTP, WebSocket). Provides comprehensive guidance for integrating Model Context Protocol servers into Claude Code plugins for

JetBrains YouTrack via Apideck's Proxy API + managed Vault auth — Apideck handles auth and proxies HTTP calls to JetBrains YouTrack's native API. Use when the user wants to call JetBrains YouTrack (no unified API resource mapping). Routes through Apideck with serviceId "jetbrains-youtrack".

Project-specific UI refactor workflow for the Scoop news platform in /home/bender/classwork/Thesis. Use when updating Scoop frontend layouts, globe UX, research workspace, and brand docs while preserving all features and enforcing a no-emoji policy across UI, logs, and docs.

Next.js 15 애플리케이션을 위한 프론트엔드 개발 가이드라인. React 19, TypeScript, Shadcn/ui, Tailwind CSS를 사용한 모던 패턴. Server Components, Client Components, App Router, 파일 구조, Shadcn/ui 컴포넌트, 성능 최적화, TypeScript 모범 사례 포함. 컴포넌트, 페이지, 기능 생성, 데이터 페칭, 스타일링, 라우팅, 프론트엔드 코드 작업 시 사용.

Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWA

Align protein structures using Foldseek 3Di, TM-align, US-align, DALI, or Foldmason for structural MSA. Predict, score, and superpose backbone coordinates when sequence identity is below the twilight zone or remote-homology detection is required. Use when sequence MSA fails (<25% identity), when the dark proteome is the target, when AlphaFoldDB / ESM Atlas search is needed, or when structural supe