DevOps e Infra

Creates reproducible Jupyter notebooks for bioinformatics analysis with parameterization using papermill. Use when generating automated analysis reports, running notebook-based pipelines, or creating shareable computational notebooks.

View, query, and understand VCF/BCF variant files using bcftools and cyvcf2. Use when inspecting variants, extracting specific fields, or understanding VCF format structure.

2D game development principles. Sprites, tilemaps, physics, camera.

Predicts ADMET properties using ADMETlab 3.0 API or DeepChem models. Estimates bioavailability, CYP inhibition, hERG liability, and 119 toxicity endpoints with uncertainty quantification. Filters for PAINS and other structural alerts. Use when filtering compounds for drug-likeness or prioritizing leads by predicted safety.

Upstash QStash expert for serverless message queues, scheduled jobs, and reliable HTTP-based task delivery without managing infrastructure. Use when: qstash, upstash queue, serverless cron, scheduled http, message queue serverless.

When the user wants to create, optimize, or audit a startups, education, or special program page. Also use when the user mentions "startups program," "for startups," "education discount," "student plan," "for students," or "special pricing." For education discounts, use education-program.

Stage and commit the current session's changes only. Session-isolated (never -A), doc-sync-gated, conventional message, offers push on explicit confirmation. Bundled with super-bootstrap — encodes the harness commit rules.

Automate Zoom meeting creation, management, recordings, webinars, and participant tracking via Rube MCP (Composio). Always search tools first for current schemas.

Comprehensive Docker containerization workflow covering multi-stage builds, docker-compose orchestration, image optimization, debugging, and production best practices. Use when containerizing applications, setting up development environments, or deploying with Docker.

Brief description of what this skill does. Use when [specific trigger situations].

Download raw sequencing reads from NCBI SRA using sra-tools (prefetch, fasterq-dump, vdb-validate) or the ENA mirror. Use when pulling FASTQ for SRR/ERR/DRR accessions, deciding between SRA-direct, ENA mirror, or AWS/GCP cloud mirror (STRIDES), handling --include-technical for 10x and other single-cell records, validating with MD5/vdb-validate, navigating SRR/SRX/SRS/SRP/PRJNA hierarchy, or findin

Plan and control time-step policies for simulations. Use when coupling CFL/physics limits with adaptive stepping, ramping initial transients, scheduling outputs/checkpoints, or planning restart strategies for long runs.