Explorar skills

Read, write, and convert phylogenetic tree files using Biopython Bio.Phylo. Use when parsing Newick, Nexus, PhyloXML, or NeXML tree formats, converting between formats, or handling multiple trees.

Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating synthetic networks, or visualizing network topologies. Applicable to social networks, biological net

Generate PPTs from topics or templates, edit existing presentations via natural language, or perform local file operations (delete/reorder/merge slides). Trigger on requests to create, modify, or manipulate .pptx files. Built on Nano Banana 2. Requires Python 3.8+.

Python testing with pytest using uv package manager. Use when: (1) Running Python tests, (2) Writing test files or test functions, (3) Setting up fixtures, (4) Parametrizing tests, (5) Generating coverage reports, (6) Testing FastAPI applications, (7) Debugging test failures, (8) Configuring pytest options. Triggers: "run tests", "write tests", "test coverage", "pytest", "unit test", "integration

Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -spl

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Python design patterns including KISS, Separation of Concerns, Single Responsibility, and composition over inheritance. Use this skill when designing a new service or component from scratch and choosing how to layer responsibilities, when refactoring a God class or monolithic function that has grown too large, when deciding whether to add a new abstraction or live with duplication, when evaluating

API + Python SDK for ordering cell-free protein expression and binding assays. Submit sequences for expression (10–100 µg), measure binding affinity (KD) against targets, track status, and retrieve results programmatically — no wet-lab setup. Built for ML-guided directed evolution and antibody/nanobody optimization. Requires Adaptyv account and API key.

End-to-end onboarding for a freshly-plugged-in M5Stack ESP32 device (Cardputer, Cardputer-Adv, Core, CoreS3, Stick) — detect on USB, flash UIFlow 2.0 firmware, and install the Claude Buddy MicroPython app bundle. Use whenever the user plugs in or wants to flash/provision/reset an M5Stack or ESP32 board, or says "m5-onboard go".

Comprehensive backend development skill for building scalable backend systems using NodeJS, Express, Go, Python, Postgres, GraphQL, REST APIs. Includes API scaffolding, database optimization, security implementation, and performance tuning. Use when designing APIs, optimizing database queries, implementing business logic, handling authentication/authorization, or reviewing backend code.

Analyze datasets to extract insights, identify patterns, and generate reports. Use when exploring data, creating visualizations, or performing statistical analysis. Handles CSV, JSON, SQL queries, and Python pandas operations.

pytest testing patterns for Python. Triggers on: pytest, fixture, mark, parametrize, mock, conftest, test coverage, unit test, integration test, pytest.raises.