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Build volcano and MA plots from differential-expression / association results with LFC shrinkage, FDR-adjusted thresholds, sensible label placement, and axis-truncation conventions. Covers EnhancedVolcano, ggplot2, matplotlib, and the apeglm/ashr/normal shrinkage decision. Use when visualizing differential-expression results (RNA-seq, ChIP-seq, ATAC-seq, proteomics) or any per-feature effect-size

This skill provides comprehensive guidance for implementing and reviewing GDPR-compliant features in Empathy Ledger.

Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / mi

Control Sonos speakers (discover/status/play/volume/group).

Sistema avançado de inteligência coletiva Hive Mind para coordenação multiagente liderada por uma rainha, com mecanismos de consenso e memória persistente.

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Deep generative models for single-cell omics. Use when you need probabilistic batch correction (scVI), transfer learning, differential expression with uncertainty, or multi-modal integration (TOTALVI, MultiVI). Best for advanced modeling, batch effects, multimodal data. For standard analysis pipelines use scanpy.

Design a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints, performance patterns, and advanced features

This skill should be used after productive sessions to extract learnings and route them to appropriate Reusable Intelligence Infrastructure (RII) components. Use when corrections were made, format drift was fixed, new patterns emerged, or the user explicitly asks to "harvest learnings" or "capture session intelligence". Transforms one-time fixes into permanent organizational knowledge by implement

Esta skill utiliza o SDK JavaScript/TypeScript do Azure Blob Storage (@azure/storage-blob) para operações como upload, download, listagem e gerenciamento de blobs e contêineres. Suporta blobs de bloco, de acréscimo e de página, tokens SAS e streaming.

Annotate VCF variants with VEP, ClinVar, gnomAD frequencies, and ancestry-aware context. Generates prioritised variant reports.

Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI. Models: GPT-Image-2, FLUX Dev LoRA, FLUX.2 Klein LoRA, Gemini 3 Pro Image, Grok Imagine, Seedream 4.5, Reve, ImagineArt. Capabilities: text-to-image, image-to-image, inpainting, LoRA, image editing, upscaling, text rendering. Use for: AI art, product mockups, concept art, social media graph