Dados e Análise

Builds multi-variant Elo rating systems for sports prediction. Use when user asks about Elo ratings, rating systems, team strength, K-factor, home field advantage, season carryover, margin-of-victory adjustments, or mentions 'Fading Elo', 'Form Elo', 'Component Elo'. Do not use for general feature construction -- see feature-engineering instead. Do not use for team stats without ratings -- see tea

Read, write, and create single-cell data objects using Seurat (R) and Scanpy (Python). Use for loading 10X Genomics data, importing/exporting h5ad and RDS files, creating Seurat objects and AnnData objects, and converting between formats. Use when loading, saving, or converting single-cell data formats.

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.

Fast CLI/Python queries to 20+ bioinformatics databases. Use for quick lookups: gene info, BLAST searches, AlphaFold structures, enrichment analysis. Best for interactive exploration, simple queries. For batch processing or advanced BLAST use biopython; for multi-database Python workflows use bioservices.

Escreva consultas de banco de dados seguras e otimizadas usando instruções parametrizadas, carregamento antecipado, indexação adequada e gerenciamento de transações.

This skill is designed to help users automatically extract business data from Google Maps search results. The Agent should proactively apply this skill when the user makes the following requests searching for coffee shops in a specific city, finding dentists or medical clinics nearby, tracking competitors' locations in a certain area, extracting business leads from Google Maps lists, gathering res

Implement MCP resources that provide data and files to AI assistants - URIs, caching, and streaming

Analyze cell-cell communication in spatial transcriptomics data using ligand-receptor analysis with Squidpy. Infer intercellular signaling, identify communication pathways, and visualize interaction networks. Use when analyzing cell-cell communication in spatial context.

Align RNA-seq reads with STAR (Spliced Transcripts Alignment to a Reference). Supports two-pass mode for novel splice junction discovery. Use when aligning RNA-seq data requiring splice-aware alignment.

This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to BED file collections, scATAC-seq data, chromatin accessibility datasets, and region-based genomic fe

Track predictions vs actuals in production: log bets, compute CLV, monitor ROI, detect edge decay, and run significance tests. Use when user asks about tracking bets, bet logging, closing line value, CLV, ROI tracking, win rate, drawdown monitoring, or whether their model has an edge right now. Do not use for finding today's bets -- see daily-card or edge-detection. Do not use for historical backt

Map nucleosome center positions, occupancy, and fuzziness from ATAC-seq fragment-size patterns using NucleoATAC, ATACseqQC, DANPOS3, or scprinter. Use when characterizing nucleosome organization at promoters and enhancers, calling +1/-1 nucleosomes flanking NFRs, generating V-plots for chromatin structure visualization, or comparing nucleosome positioning between conditions.