Dados e Análise

Query Metabolomics Workbench REST API (4,200+ NIH studies) for metabolite ID, study discovery, RefMet standardization, m/z precursor searches, and gene/protein annotations. Quirks: compound input_item rejects `name` (use pubchem_cid/kegg_id/inchi_key/etc.); free-text → compound is a two-step refmet/match→refmet/name flow; moverz endpoint returns TSV text, not JSON. Use hmdb-database for local XML;

Padrões de arquitetura de backend, design de API, otimização de banco de dados e melhores práticas de servidor para Node.js, Express e rotas de API do Next.js.

AI-powered RNA velocity analysis for predicting cellular state transitions, differentiation trajectories, and dynamic gene regulation from single-cell RNA sequencing data.

Create and edit Obsidian Bases (.base files) with views, filters, formulas, and summaries. Use when working with .base files, creating database-like views of notes, or when the user mentions Bases, table views, card views, filters, or formulas in Obsidian.

Use quando o usuário quiser chamar a Produção de Dados de Mercado Schwab via o servidor schwab-marketdata-mcp, solucionar problemas de OAuth ou expiração de token de atualização de 7 dias, recuperar-se de erros 401/429/5xx, ou consultar o esquema exato de entrada/saída para qualquer uma das 12 ferramentas de dados de mercado (quotes×2, price_history, option_chain×2, market_hours×2, movers, search_instruments, get_instrument_by_cusip, health_check, get_server_info).

End-to-end bisulfite sequencing workflow from FASTQ to differentially methylated regions. Covers Bismark alignment, methylation calling, and DMR detection with methylKit. Use when analyzing bisulfite sequencing data.

Cheminformatics toolkit for molecular analysis and virtual screening: SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints (Morgan/ECFP, MACCS), Tanimoto similarity, SMARTS substructure filtering, Lipinski drug-likeness, reaction enumeration, 2D/3D coordinates. For simpler API use datamol; use RDKit for fine-grained sanitization, custom fingerprints, or SMARTS/reaction control.

API key for MaxHub data APIs. Get one at https://www.aconfig.cn

Database migration best practices for schema changes, data migrations, rollbacks, and zero-downtime deployments across PostgreSQL, MySQL, and common ORMs (Prisma, Drizzle, Kysely, Django, TypeORM, golang-migrate).

Analyzes CUT&RUN (Skene Henikoff 2017) and CUT&Tag (Kaya-Okur 2019) chromatin profiling data. Handles SEACR vs MACS2 peak calling (with the btaf375 2025 benchmark guidance), pA-MNase vs pA-Tn5 vs pAG-Tn5 chimera differences, E. coli spike-in carryover normalization, IgG-only control logic (no input), characteristic fragment-size signatures (25-75 bp for CUT&Tag), and lower depth requirements (5M r

When the user needs to draft, review, or update a privacy policy for their product, or needs to understand data privacy obligations across jurisdictions.

Comprehensive Excel spreadsheet creation, editing, and analysis with support for formulas, formatting, charts, data analysis, and visualization. Use when working with .xlsx, .xlsm, .csv files for: (1) Creating spreadsheets with formulas and formatting, (2) Reading/analyzing data, (3) Modifying existing spreadsheets while preserving formulas, (4) Creating charts and visualizations, (5) Data transfo