Dados e Análise

Convert between gene identifier systems including Ensembl, Entrez, HGNC symbols, and UniProt. Use when mapping IDs for pathway analysis or matching different data sources.

Segments the genome into chromatin states from combinatorial histone modification and chromatin factor ChIP-seq data. Uses ChromHMM (multivariate HMM on binarized signal, v1.27), Segway (Dynamic Bayesian Network on continuous signal), EpiSegMix (flexible-distribution HMM with duration modeling, 2024), EpiLogos (multi-biosample visualization), IDEAS (cell-type-aware joint), and full-stack ChromHMM

Deep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Illumina, PacBio, and ONT data. Use when calling variants with DeepVariant deep learning caller.

Query the Ensembl REST API for gene/transcript/protein lookup, sequence retrieval, comparative genomics (Compara), variant effect prediction (VEP), regulatory features, and cross-species ortholog/paralog calls. Use when pulling Ensembl-native data (Ensembl Gene IDs, version-pinned releases, archive endpoints for reproducibility), gene/transcript/exon structure with stable IDs, or VEP for variant a

O SDK de Consulta do Azure Monitor para Python permite consultar workspaces do Log Analytics e métricas do Azure Monitor, suportando consultas Kusto e clientes como LogsQueryClient.

Jira Data Center via Apideck's Proxy API + managed Vault auth — Apideck handles auth and proxies HTTP calls to Jira Data Center's native API. Use when the user wants to call Jira Data Center (no unified API resource mapping). Routes through Apideck with serviceId "jira-data-center".

Omics data forge

Call structural variants (SVs) from sequencing data using Manta, Delly, GRIDSS, and LUMPY. Detects deletions, insertions, inversions, duplications, and translocations too large for standard SNV callers. Use when detecting structural variants from short-read or long-read data and building consensus callsets.

Quantum mechanics simulations and analysis using QuTiP (Quantum Toolbox in Python). Use when working with quantum systems including: (1) quantum states (kets, bras, density matrices), (2) quantum operators and gates, (3) time evolution and dynamics (Schrödinger, master equations, Monte Carlo), (4) open quantum systems with dissipation, (5) quantum measurements and entanglement, (6) visualization (

Expert SQL query writing, optimization, and database schema design with support for PostgreSQL, MySQL, SQLite, and SQL Server. Use when working with databases for: (1) Writing complex SQL queries with joins, subqueries, and window functions, (2) Optimizing slow queries and analyzing execution plans, (3) Designing database schemas with proper normalization, (4) Creating indexes and improving query

Use this skill when designing or reviewing a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints, performance patterns, and advanced features

Expert in Langfuse - the open-source LLM observability platform. Covers tracing, prompt management, evaluation, datasets, and integration with LangChain, LlamaIndex, and OpenAI. Essential for debugging, monitoring, and improving LLM applications in production. Use when: langfuse, llm observability, llm tracing, prompt management, llm evaluation.