Dados e Análise

Load, convert, and manipulate Hi-C contact matrices using cooler format. Read .cool/.mcool files, convert from .hic format, access matrix data, and export to different formats. Use when loading or converting Hi-C contact matrices.

Parallel/distributed computing. Scale pandas/NumPy beyond memory, parallel DataFrames/Arrays, multi-file processing, task graphs, for larger-than-RAM datasets and parallel workflows.

API key for MaxHub data APIs. Get one at https://www.aconfig.cn

Build publication-quality figures in R with ggplot2 using the grammar of graphics (data + aesthetics + geometries + scales + facets + themes) with CVD-safe palettes, cairo_pdf TrueType embedding, programmatic aes via tidy evaluation, and the theme_classic publication baseline. Use when producing static figures in R for papers, presentations, or reports.

分析一段时间内健康数据的趋势和模式。关联药物、症状、生命体征、化验结果和其他健康指标的变化。识别令人担忧的趋势、改善情况，并提供数据驱动的洞察。当用户询问健康趋势、模式、随时间的变化或"我的健康状况有什么变化？"时使用。支持多维度分析（体重/BMI、症状、药物依从性、化验结果、情绪睡眠），相关性分析，变化检测，以及交互式HTML可视化报告（ECharts图表）。

Query the ClinPGx (formerly PharmGKB) REST API plus the CPIC PostgREST companion API for pharmacogenomic clinical annotations, CPIC/DPWG dosing guidelines, gene-drug pairs, variant-drug associations, FDA/EMA drug labels, and PGx pathways. Two-host architecture: api.clinpgx.org for annotation records, api.cpicpgx.org for genotype→recommendation lookups. No auth. For germline pathogenicity use clinv

Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.

Automate Google Analytics tasks via Rube MCP (Composio): run reports, list accounts/properties, funnels, pivots, key events. Always search tools first for current schemas.

"Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity.

Teaches how to use Claude and MCP tools effectively for hockey analytics -- exploratory analysis, hypothesis testing, model iteration, and report generation. Use when user asks how to analyze hockey data with AI, how to structure an analysis session, how to test a hypothesis about team or player performance, how to improve a model systematically, or how to generate a performance report. Do not use

Inferir redes reguladoras de genes (GRNs) a partir de dados de expressão gênica usando algoritmos escaláveis (GRNBoost2, GENIE3). Use para analisar dados transcriptômicos (RNA-seq em massa, RNA-seq de célula única) e identificar relações entre fatores de transcrição e genes-alvo, além de interações regulatórias, com suporte a computação distribuída para grandes conjuntos de dados.

Generate presentation layer code (Freezed states, Riverpod notifiers, screens, widgets) from feature specifications. Creates the UI layer with proper state management. Use after /data to implement screens and state handling.