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Comprehensive git worktree management. Use when the user wants to create, remove, list, or manage worktrees. Handles all worktree operations including creation, deletion, and status checking.

Build and analyze phylogenetic trees using MAFFT (multiple alignment), IQ-TREE 2 (maximum likelihood), and FastTree (fast NJ/ML). Visualize with ETE3 or FigTree. For evolutionary analysis, microbial genomics, viral phylodynamics, protein family analysis, and molecular clock studies.

This skill should be used at the start of any computationally intensive scientific task to detect and report available system resources (CPU cores, GPUs, memory, disk space). It creates a JSON file with resource information and strategic recommendations that inform computational approach decisions such as whether to use parallel processing (joblib, multiprocessing), out-of-core computing (Dask, Za

Pythonic idioms, PEP 8 standards, type hints, and best practices for building robust, efficient, and maintainable Python applications.

Create or update a shared Apple design context document that other HIG skills use to tailor guidance. Use when the user says 'set up my project context,' 'what platforms am I targeting,' 'configure HIG settings,' or when starting a new Apple platform project.

Call structural variants (SVs) from short-read sequencing using Manta, Delly, and LUMPY. Detects deletions, insertions, inversions, duplications, and translocations that are too large for standard SNV callers. Use when detecting structural variants from short-read data.

Revisão e fortalecimento de políticas IAM, e implementação do princípio do menor privilégio.

Ancestry analysis report with population assignments and statistics

Provide differential diagnosis for patients with suspected rare diseases based on phenotype and genetic data. Matches symptoms to HPO terms, identifies candidate diseases from Orphanet/OMIM, prioritizes genes for testing, interprets variants of uncertain significance. Use when clinician asks about rare disease diagnosis, unexplained phenotypes, or genetic testing interpretation.

X/Twitter API integration for posting tweets, threads, reading timelines, search, and analytics. Covers OAuth auth patterns, rate limits, and platform-native content posting. Use when the user wants to interact with X programmatically.

Create AI avatar and talking head videos via inference.sh CLI. Recommended: P-Video-Avatar (fastest, cheapest, built-in TTS). Also: OmniHuman, Fabric, PixVerse. Audio: Inworld TTS-2 (100+ languages, emotion steering for characters), ElevenLabs, Kokoro. Capabilities: audio-driven avatars, text-to-avatar, lipsync videos, talking head generation, virtual presenters, UGC content. Use for: AI presenter

Detect patterns, anomalies, and trends in code and data. Use when identifying code smells, finding security vulnerabilities, or discovering recurring patterns. Handles regex patterns, AST analysis, and statistical anomaly detection.