DevOps e Infra

Fundamentos de script Bash para bioinformática: variáveis, condicionais, loops e padrões de pipeline.

Regiões Diferencialmente Metiladas (DMRs)

Identify underspecified areas in the current feature spec by asking up

Modelagem Molecular com NumPy

Da Variação de DNA à Estrutura Proteica: AlphaFold2, AlphaFold3, RoseTTAFold com NumPy

Análise de redes biológicas, utilizando redes PPI do STRING, métricas de grafo NetworkX e detecção de comunidades Louvain. Realiza enriquecimento GO por módulo, exportação para Cytoscape e inferência de redes regulatórias gênicas com GENIE3.

Modelos de Fundação Genômicos: Nucleotide Transformers, HyenaDNA e Evo com NumPy.

This skill should be used when the user asks to audit, health-check, or structurally validate one or more SPECIFIC named notes or a bounded topic cluster — 'audit these notes', 'check this note for orphans or broken links', 'fourth-wall check on [note]', 'validate the structure of [note]', 'spot-check [note]'. Runs a read-only audit inline. NOT for fixing issues (use /knowledge-maintain), NOT for

Tracks and reports token usage and dollar cost across every level of a vibe-* project — per task, per session, per feature, per phase, and total project spend. Auto-runs at the end of every session with estimates. When invoked manually with "cost:" accepts pasted Claude Code /cost output for precise numbers. Detects eight waste patterns: CP-01 context overhead, CP-02 repeated reads, CP-03 unstruct

Spec quality gate — audits planning documents before any code is written. Automatically triggered by vibe-brainstorm (after BRIEF.md), vibe-agent (after AGENT_ARCH.md), vibe-new-app and vibe-init (after vibe/ folder), and vibe-add-feature (after FEATURE_SPEC.md). Audits all documents that exist: BRIEF.md, AGENT_ARCH.md, SPEC.md, ARCHITECTURE.md, FEATURE_SPEC.md. P0 findings are critical gaps that

Modelos de Splicing: SpliceAI e AlphaGenome com NumPy

Use when evaluating projects for production or enterprise readiness, implementing supply chain security (SLSA, cosign, SBOMs, pnpm), hardening CI/CD pipelines, establishing quality gates (TYPO3: CI matrix PHP 8.2-8.5 x TYPO3 12.4/13.4/14.3 LTS), pursuing OpenSSF Best Practices Badge (Passing/Silver/Gold) or OSPS Baseline levels, reviewing code quality, writing ADRs, or configuring Git hooks and CI